Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about UBIQUILIN2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | UBIQUILIN2 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 66 kDa |
| Amino Acids | 624 aa |
| GeneCards | UBIQUILIN2 |
| Human Protein Atlas | UBIQUILIN2 |
| UBA domain (C-terminal) | The ubiquitin-associated domain (residues 577–624) binds polyubiquitin chains on misfolded or damaged proteins, recognizing them as substrates for degradation [@ubiquilin2014]. |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
UBIQUILIN2["UBIQUILIN2"]
neurodegeneration["neurodegeneration"]
UBIQUILIN2 -->|"implicated_in"| neurodegeneration
style UBIQUILIN2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning UBIQUILIN2 in their description or question text
No additional research found