Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about UBQLN4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | UBQLN4 |
| Chromosome | Xq24 |
| Function | is a gene located on chromosome Xq24 that encodes a member of the ubiquilin family of proteins involved in protein quality control and degradation pathways. |
| Primary Expression | Motor cortex, Hippocampus, Cerebellum |
| Amino Acids | 624 aa |
| UniProt ID | Q9Y5X5 |
| Ensembl ID | ENSG00000163527 |
| OMIM | 300368 |
| GeneCards | UBQLN4 |
| Human Protein Atlas | UBQLN4 |
| Symbol [@neuronal2019] UBQLN4 [@proteasome2017] [@autophagy2020] [@vcp2018] Full Name [@ubqln2020] Ubiquilin 4 [@ubqln2020a] [@nuclear2021] [@tdp2019] Chromosome [@recessive2018] Xq24 NCBI Gene | 94160 |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
UBQLN4["UBQLN4"]
neurodegeneration["neurodegeneration"]
UBQLN4 -->|"implicated_in"| neurodegeneration
style UBQLN4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||