UNG

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolUNG
Nameuracil DNA glycosylase
Typeprotein-coding
Sourcemygene

Summary

This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used

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This is an externally resolved entity

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