gene

UQCRQ

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about UQCRQ: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for UQCRQ

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🧬 Gene Info

Gene Symbol	UQCRQ
Protein Type	Gene
Function	encodes a histone H3 lysine 4 (H3K4) methyltransferase, a critical epigenetic enzyme involved in transcriptional regulation and chromatin remodeling.
Primary Expression	the brain:
Amino Acids	700 aa
GeneCards	UQCRQ
Human Protein Atlas	UQCRQ
SET domain	The catalytic domain responsible for methyltransferase activity[@shilatifard2012]
NRM domain	Involved in complex formation and substrate recognition
SANT domains	Chromatin-interacting domains that facilitate histone binding
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

UQCRQ

gene · 708 words

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Pathway Diagram

graph TD
    UQCRQ["UQCRQ"]
    neurodegeneration["neurodegeneration"]
    UQCRQ -->|"implicated_in"| neurodegeneration
    style UQCRQ fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning UQCRQ in their description or question text

No additional research found