gene

USH1G

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about USH1G: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	USH1G
Full Name	USHER Syndrome 1G Protein (SANS)
Chromosome	17q25.1
Protein Type	Gene
Function	is a critical gene involved in the development and maintenance of the auditory and visual systems.
Primary Expression	both inner and outer hair cells of the cochlea - Stereocilia: Localizes to the stereociliary tips and shafts - Vestibular system: Present in h
Molecular Weight	51 kDa
Amino Acids	460 aa
GeneCards	USH1G
Human Protein Atlas	USH1G
Ankyrin (ANK) repeat domain	Three ankyrin repeats (residues 50-180) that mediate protein-protein interactions
SAM (Sterile Alpha Motif) domain	Located in the central region (residues 200-260)
PDZ-binding motif	The extreme C-terminus contains a canonical PDZ-binding sequence (S/T-X-L/V)
Hair cells	Expressed in both inner and outer hair cells of the cochlea
Stereocilia	Localizes to the stereociliary tips and shafts
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

USH1G — USHER Syndrome 1G Protein (SANS)

gene · 3073 words

→

USH1G Protein

protein · 748 words

→

Pathway Diagram

graph TD
    USH1G["USH1G"]
    neurodegeneration["neurodegeneration"]
    USH1G -->|"implicated_in"| neurodegeneration
    style USH1G fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning USH1G in their description or question text

No additional research found