USP15

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolUSP15
Nameubiquitin specific peptidase 15
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants enc

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