Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about USP24: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | USP24 |
| Chromosome | 1p31.3 |
| Protein Type | Gene |
| Function | USP24 performs critical functions in cellular homeostasis: [@blauwendraat2019] |
| Primary Expression | various brain regions: [@lill2015] |
| Molecular Weight | 280 kDa |
| Amino Acids | 600 aa |
| Exons | Multiple alternatively spliced isoforms |
| Pathways | NF-κB, Wnt |
| GeneCards | USP24 |
| Human Protein Atlas | USP24 |
| Position | Approximately 1p31.3 region |
| Strand | Plus strand |
| N-terminal Domain | Contains multiple USP domains |
| catalytic Core Domain | Contains the USP domain with cysteine protease activity |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
USP24["USP24"]
neurodegeneration["neurodegeneration"]
USP24 -->|"implicated_in"| neurodegeneration
style USP24 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning USP24 in their description or question text
No additional research found