gene

VAMP5

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about VAMP5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🧬 Gene Info

Gene Symbol	VAMP5
Full Name	Vesicle Associated Membrane Protein 5 (Synaptobrevin-2)
Chromosome	2p23.3
Function	encodes a 116-amino acid integral membrane protein that is predominantly expressed in neuronal cells, where it functions as a v-SNARE (vesicle SNARE) essential for neurotransmitter release.
Primary Expression	neuronal cells, where it functions as a v-SNARE (vesicle SNARE) essential for neurotransmitter release
Molecular Weight	13 kDa
Amino Acids	116 aa
Exons	5
UniProt ID	Q9YB91
NCBI Gene ID	10791
Ensembl ID	ENSG00000184979
OMIM	608352
GeneCards	VAMP5
Human Protein Atlas	VAMP5
SNARE motif	16-layer coiled-coil structure critical for complex formation
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: VAMP5 — AlphaFold Q9YB91 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

VAMP5 — Vesicle Associated Membrane Protein 5 (Synaptobrevin-2)

gene · 1565 words

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Pathway Diagram

graph TD
    VAMP5["VAMP5"]
    neurodegeneration["neurodegeneration"]
    VAMP5 -->|"implicated_in"| neurodegeneration
    style VAMP5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning VAMP5 in their description or question text

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