gene

VFRM

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about VFRM: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

Vimentin receptor - functions as receptor for vimentin intermediate filament

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	VFRM
Full Name	Vimentin Receptor
Chromosome	5q31.2
Protein Type	Receptor
Function	VFRM functions as a receptor for vimentin, mediating several cellular processes:
Pathways	PI3K, MAPK
UniProt ID	Q9Y4F9
NCBI Gene ID	10670
Ensembl ID	ENSG00000165376
OMIM	614519
GeneCards	VFRM
Human Protein Atlas	VFRM
FAK activation	Focal adhesion kinase phosphorylation triggers downstream signaling cascades controlling cell migration and survival
Src family kinases	Activation of Src family members including Fyn and Lyn modulates cytoskeletal dynamics and synaptic function
PI3K/Akt pathway	Modulation of cell survival, proliferation, and metabolic signaling
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: VFRM — AlphaFold Q9Y4F9 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

VFRM Gene

gene · 1847 words

→

Pathway Diagram

graph TD
    VFRM["VFRM"]
    neurodegeneration["neurodegeneration"]
    VFRM -->|"implicated_in"| neurodegeneration
    style VFRM fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning VFRM in their description or question text

No additional research found