gene

VGLUV1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about VGLUV1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

VGLUT1 Gene

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🧬 Gene Info

Gene Symbol	VGLUV1
Chromosome	19q13.33
Function	is a multipass transmembrane protein with 12 predicted transmembrane domains.
Primary Expression	Cortex, Hippocampus, Cerebellum
Molecular Weight	62 kDa
Amino Acids	560 aa
Exons	12
UniProt ID	[Q9P2U7](https://www.uniprot.org/uniprot/Q9P2U7)
Ensembl ID	ENSG00000177508
GeneCards	VGLUV1
Human Protein Atlas	VGLUV1
VGLUT1 (SLC17A7)	Cortex, hippocampus, cerebellar cortex — predominant in adults
VGLUT2 (SLC17A6)	Thalamus, brainstem, hypothalamus — predominant in developing brain
VGLUT3 (SLC17A8)	Serotonergic neurons, cholinergic neurons, pineal gland — co-released with other neurotransmitters
N-terminus	Cytoplasmic, contains regulatory motifs
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

VGLUT1 Gene

gene · 1468 words

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Pathway Diagram

graph TD
    VGLUV1["VGLUV1"]
    neurodegeneration["neurodegeneration"]
    VGLUV1 -->|"implicated_in"| neurodegeneration
    style VGLUV1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning VGLUV1 in their description or question text

No additional research found