Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about VIPR1PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Receptor for vasoactive intestinal peptide (VIP), involved in neuroprotection, immune modulation, and circadian rhythm regulation. This protein plays important roles in cellular signaling pathways relevant to neurodegenerative disease pathogenesis.
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| Gene Symbol | VIPR1PROTEIN |
| Protein Type | Receptor |
| Function | is a Secretin receptor family (Class B GPCR) member involved in Receptor for vasoactive intestinal peptide (VIP), involved in neuroprotection, immune modulation, and circadian rhythm regulation. |
| Subcellular Localization | ## Disease Associations ### Alzheimer's Disease Vipr1 is implicated in Alzheim |
| Molecular Weight | 50 kDa |
| GeneCards | VIPR1PROTEIN |
| Human Protein Atlas | VIPR1PROTEIN |
| Extracellular domain | Ligand binding |
| Transmembrane domains | 7TM architecture (for GPCR family) |
| Intracellular domain | G-protein coupling and signaling |
| N-glycosylation | Affects ligand binding and trafficking |
| Phosphorylation | Modulates receptor activity |
| Palmitoylation | Affects membrane localization |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
VIPR1PROTEIN["VIPR1PROTEIN"]
neurodegeneration["neurodegeneration"]
VIPR1PROTEIN -->|"implicated_in"| neurodegeneration
style VIPR1PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
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Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning VIPR1PROTEIN in their description or question text
No additional research found