WIPI2

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolWIPI2
NameWD repeat domain, phosphoinositide interacting 2
Typeprotein-coding
Sourcemygene

Summary

WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008].

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