Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about WNT10B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | WNT10B |
| Chromosome | 12q13.12 |
| Function | is a protein-coding gene encoding a secreted signaling molecule critical for embryonic development, tissue homeostasis, and cellular differentiation. |
| Molecular Weight | 42 kDa |
| Amino Acids | 30 aa |
| Pathways | WNT, Wnt, Wnt signaling, Wnt pathway |
| UniProt ID | Q9Y5Q1 |
| NCBI Gene ID | 7480 |
| Ensembl ID | ENSG00000169884 |
| OMIM | 605397 |
| GeneCards | WNT10B |
| Human Protein Atlas | WNT10B |
| Signal peptide | N-terminal 25-30 amino acids for secretion |
| Wnt domain | Conserved ~350 amino acid signaling domain |
| 12 conserved cysteine residues | Form disulfide bonds |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
WNT10B["WNT10B"]
neurodegeneration["neurodegeneration"]
WNT10B -->|"implicated_in"| neurodegeneration
style WNT10B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning WNT10B in their description or question text
No additional research found