gene

WNT5B

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about WNT5B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Comprehensive gene profile for WNT5B (WNT Family Member 5B), a key ligand in Wnt signaling with roles in neural development, synaptic plasticity, and neurodegenerative disease.

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🧬 Gene Info

Gene Symbol	WNT5B
Full Name	WNT Family Member 5B
Chromosome	12p13.33
Protein Family	Wnt family (WNT5B is a ligand)
Function	is a secreted glycoprotein that functions as a ligand in the Wnt signaling pathway.
Primary Expression	Brain, spinal cord, lung, pancreas, kidney
Molecular Weight	40 kDa
Pathways	WNT, Wnt, Wnt signaling, wnt
UniProt ID	Q9H1J7
NCBI Gene ID	64640
Ensembl ID	ENSG00000173230
OMIM	609351
GeneCards	WNT5B
Human Protein Atlas	WNT5B
Vangl2	Core PCP component that regulates cellular polarity
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: WNT5B — AlphaFold Q9H1J7 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

WNT5B Gene

gene · 1930 words

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Pathway Diagram

graph TD
    WNT5B["WNT5B"]
    neurodegeneration["neurodegeneration"]
    WNT5B -->|"implicated_in"| neurodegeneration
    style WNT5B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning WNT5B in their description or question text

No additional research found