gene

WNT8B

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about WNT8B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for WNT8B Gene

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🧬 Gene Info

Gene Symbol	Wingless-Type MMTV Integration Site Family Member 8B
Chromosome	10p26.3
Function	is a gene encoding a secreted signaling protein that plays crucial roles in embryonic development, neuronal differentiation, and adult brain function.
Amino Acids	350 aa
Gene Type	Protein Coding
Pathways	WNT, Wnt signaling, Wnt, Wnt pathway
UniProt ID	Q9Y5Q2
NCBI Gene ID	7479
Ensembl ID	ENSG00000070193
OMIM	605396
N-terminal signal peptide	Directs secretion
Wnt domain	~350 amino acids, the functional core
Multiple cysteine residues	Form disulfide bonds for proper folding
Lipid modification site	C-terminal palmitoylation essential for signaling
Brain	High expression in developing and adult brain
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: WNT8B — AlphaFold Q9Y5Q2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

WNT8B Gene

gene · 663 words

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Pathway Diagram

graph TD
    WNT8B["WNT8B"]
    neurodegeneration["neurodegeneration"]
    WNT8B -->|"implicated_in"| neurodegeneration
    style WNT8B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning WNT8B in their description or question text

No additional research found