gene

WNT9B

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about WNT9B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Debates

Summary

The WNT9B gene encodes Wnt-9b, a member of the Wnt signaling family involved in embryonic development, neurogenesis, and craniofacial formation. This page covers its role in canonical and non-canonical Wnt pathways, developmental biology, and potential connections to neurodegenerative diseases.

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🧬 Gene Info

Gene Symbol	WNT9B
Full Name	WNT Family Member 9B
Chromosome	17q21.2
Protein Family	Wnt family (Wnt-1 subclass)
Function	encodes a secreted glycoprotein of approximately 42 kDa.
Molecular Weight	42 kDa
Amino Acids	372 aa
Pathways	WNT, Wnt
UniProt ID	[O00144](https://www.uniprot.org/uniprot/O00144)
Ensembl ID	ENSG00000179632
OMIM	604318
GeneCards	WNT9B
Human Protein Atlas	WNT9B
Wnt-1 subclass	Wnt1, Wnt2, Wnt3, Wnt3A, Wnt9B
Wnt-5A subclass	Wnt5A, Wnt5B, Wnt11
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

WNT9B Gene

gene · 1400 words

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Pathway Diagram

graph TD
    WNT9B["WNT9B"]
    neurodegeneration["neurodegeneration"]
    WNT9B -->|"implicated in"| neurodegeneration
    Neurodegenerative_Diseases{"Neurodegenerative Diseases"}
    WNT9B -->|"implicated in"| Neurodegenerative_Diseases
    style WNT9B fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
    style Neurodegenerative_Diseases fill:#4a1a1a,stroke:#ef5350,stroke-width:1px,color:#ef5350

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning WNT9B in their description or question text

No additional research found