gene

ZDHHC14

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ZDHHC14: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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Summary

Comprehensive review of ZDHHC14, a palmitoyltransferase expressed in brain, implicated in synaptic function, estrogen signaling, and neurodegenerative disease

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🧬 Gene Info

Gene Symbol	ZDHHC14
Full Name	Zinc Finger DHHC-Type Containing 14
Chromosome	6q24.2
Protein Family	DHHC Palmitoyltransferase Family[@dhhc_family]
Protein Type	Transferase
Function	is a human gene located on chromosome 6q24.
Primary Expression	Cortex, Hippocampus, Cerebellum, Amygdala, Spinal cord
Subcellular Localization	2. DHHC domain: The catalytic core containing the essential cysteine
Amino Acids	556 aa
UniProt ID	Q8N5C4
NCBI Gene ID	203523
Ensembl ID	ENSG00000157766
OMIM	612271
GeneCards	ZDHHC14
Human Protein Atlas	ZDHHC14
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: ZDHHC14 — AlphaFold Q8N5C4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

ZDHHC14 — Zinc Finger DHHC-Type Containing 14

gene · 2471 words

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Genes

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Pathway Diagram

graph TD
    ZDHHC14["ZDHHC14"]
    neurodegeneration["neurodegeneration"]
    ZDHHC14 -->|"implicated_in"| neurodegeneration
    style ZDHHC14 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity