Entity Detail โ Knowledge Graph Node
This page aggregates everything SciDEX knows about ZNRNP1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
ZNRNP1 is an RNA-binding protein involved in RNA processing, splicing, and translation. Implicated in neurodegenerative diseases including ALS, FTD, and AD.
| Gene Symbol | ZNRNP1 |
| Full Name | Zinc Finger, RNGTT Type 1 |
| Chromosome | 5q31.2 |
| Function | is an RNA-binding protein that plays crucial roles in post-transcriptional gene regulation. |
| Primary Expression | Ubiquitous, high in brain and testis |
| Amino Acids | 576 aa |
| Exons | 12 |
| Ensembl ID | ENSG00000126752 |
| OMIM | 611075 |
| GeneCards | ZNRNP1 |
| Human Protein Atlas | ZNRNP1 |
| Associated Diseases | neurodegeneration |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["ZNRNP1"]
N1["TREM2"]
N0 -->|"upregulates"| N1
N2["neurodegeneration"]
N0 -->|"implicated in"| N2
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 gene| Target | Relation | Type | Str |
|---|---|---|---|
| TREM2 | upregulates | gene | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||