protein

adarb1-protein

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about adarb1-protein: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses
0Analyses
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🔬 Protein Info
Gene SymbolADARB1
Aliasesadarb1-protein
Protein FamilyADAR family
FunctionGluR2 Q/R site editing: Essential editing of the AMPA receptor GluR2 (GRIA2) subunit at the Q/R site. Unedited GluR2 permits Ca²⁺ influx, leading to excitotoxicity
Subcellular LocalizationNucleus (nucleolus)
Molecular Weight~70 kDa
Amino Acids739 aa
GeneCardsADARB1
Human Protein AtlasADARB1
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (2)

Knowledge base pages for this entity

ADARB1 Protein (Adenosine Deaminase Acting on RNA 1)

protein · 1192 words

ADAR Protein

protein · 727 words

Pathway Diagram

graph TD
    A["Gene expression"] --> B["adarb1 protein"]
    B --> C["Protein folding and<br/>quality control"]
    B --> D["Cellular signaling"]
    C --> E["Proteostasis"]
    D --> F["Neurotoxicity"]
    E --> G["Disease outcome"]
    F --> G
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class B protein
    class G disease

Outgoing (0)

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No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found