Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about als-ftd-spectrum: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
graph TD
als_ftd_spectrum["als-ftd-spectrum"]
HNRNPK["HNRNPK"]
als_ftd_spectrum -->|"degrades"| HNRNPK
COMPLEMENT["COMPLEMENT"]
als_ftd_spectrum -->|"interacts_with"| COMPLEMENT
ALS["ALS"]
als_ftd_spectrum -->|"regulates"| ALS
CRH["CRH"]
als_ftd_spectrum -->|"expressed_in"| CRH
CATHEPSINS["CATHEPSINS"]
als_ftd_spectrum -->|"activates"| CATHEPSINS
CH25H["CH25H"]
als_ftd_spectrum -->|"transports"| CH25H
P38["P38"]
als_ftd_spectrum -->|"contributes_to"| P38
als_ftd_spectrum -->|"activates"| ALS
als_ftd_spectrum -->|"encodes"| ALS
als_ftd_spectrum -->|"implicated_in"| ALS
C9ORF72_REPEAT_EXPANSION["C9ORF72 REPEAT EXPANSION"]
als_ftd_spectrum -->|"expressed_in"| C9ORF72_REPEAT_EXPANSION
als_ftd_spectrum -->|"activates"| ALS
style als_ftd_spectrum fill:#ef5350,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
style HNRNPK fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style COMPLEMENT fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style ALS fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style CRH fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style CATHEPSINS fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style CH25H fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style P38 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style C9ORF72_REPEAT_EXPANSION fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||