AMYLOID

Understanding Entity Pages

This page aggregates everything SciDEX knows about AMYLOID: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

AMYLOID is a gene implicated in neurodegeneration research. Key relationships include: associated with, activates, inhibits. Associated with ALS, ALZHEIMER, ALZHEIMER'S. Connected to 2116 entities in the SciDEX knowledge graph.

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graph TD
    subgraph Pathology["Pathology"]
        AMYLOID["AMYLOID"] -->|"associated with"| MICROGLIA["MICROGLIA"]
        AMYLOID["AMYLOID"] -->|"associated with"| TAU["TAU"]
        AMYLOID["AMYLOID"] -->|"associated with"| BACE1["BACE1"]
        AMYLOID["AMYLOID"] -->|"associated with"| AUTOPHAGY["AUTOPHAGY"]
        AMYLOID["AMYLOID"] -->|"associated with"| APOPTOSIS["APOPTOSIS"]
        AMYLOID["AMYLOID"] -->|"associated with"| GFAP["GFAP"]
        AMYLOID["AMYLOID"] -->|"associated with"| NEURON["NEURON"]
        AMYLOID["AMYLOID"] -->|"associated with"| SOD1["SOD1"]
        AMYLOID["AMYLOID"] -->|"associated with"| NLRP3["NLRP3"]
        AKT["AKT"] -->|"associated with"| AMYLOID["AMYLOID"]
    end
    subgraph Signaling["Signaling"]
        OXIDATIVE_STRESS["OXIDATIVE STRESS"] -->|"activates"| AMYLOID["AMYLOID"]
        ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"] -->|"activates"| AMYLOID["AMYLOID"]
        ALZHEIMER["ALZHEIMER"] -->|"activates"| AMYLOID["AMYLOID"]
        ALZHEIMER_S_DISEASE_1["ALZHEIMER'S DISEASE"] -.->|"inhibits"| AMYLOID["AMYLOID"]
        ALZHEIMER_2["ALZHEIMER"] -.->|"inhibits"| AMYLOID["AMYLOID"]
    end
    style AMYLOID fill:#4a1a6b,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0,font-weight:bold
    style MICROGLIA fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style TAU fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style BACE1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style AUTOPHAGY fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style APOPTOSIS fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style GFAP fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style NEURON fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style SOD1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style NLRP3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style AKT fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style OXIDATIVE_STRESS fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style ALZHEIMER_S_DISEASE fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style ALZHEIMER fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style ALZHEIMER_S_DISEASE_1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0
    style ALZHEIMER_2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:1px,color:#e0e0e0