Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about amyloid production: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| APP processing | causes | pathway | 0.90 |
| PSEN2 | no change | gene | 0.80 |
| wakefulness | causes | process | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Excess orexin-A worsens AD cognition through wake-driven amy | 0.711 | neurodegeneration | Orexin-A manipulation in AD cognition an |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-26 | 3 hypotheses Top: 0.758
connectomics | 2026-04-16 | 13 hypotheses Top: 0.535
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.78 · 2026-04-26
closed · Rounds: 4 · Score: 0.50 · 2026-04-18
Hypotheses and analyses mentioning amyloid production in their description or question text
No additional research found