PAFAH1B3

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPAFAH1B3
Nameplatelet activating factor acetylhydrolase 1b catalytic subunit 3
Typeprotein-coding
Sourcemygene

Summary

This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and w

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