Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about cathepsin_B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
| Target | Relation | Type | Str |
|---|---|---|---|
| tau_truncation | regulates | mechanism | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| PD-Associated GWAS Variants in CTSO and CTSF Genes Create a | 0.743 | neurodegeneration | - |
| Dual Calpain/Cathepsin B Inhibition as Primary Neuroprotecti | 0.644 | neurodegeneration | Why does autophagy inhibition improve ne |
| Selective cathepsin B inhibition prevents cathepsin leakage- | 0.620 | neuroscience | Lysosomal dysfunction and cathepsin leak |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-11 | 0 hypotheses
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning cathepsin_B in their description or question text
No additional research found