cell 1,570 words KG: ent-gene-e3e99452
Contents

Synaptophysin Neurons

🔬 Protein Info
Gene Symbolent-gene-e3e99452
Four transmembrane domainsForm a barrel-like structure that spans the synaptic vesicle membrane
Cytoplasmic C-terminal tailContains phosphorylation sites that regulate protein interactions
N-terminal luminal domainExposed on the outer surface of synaptic vesicles
SYP1The canonical isoform, widely expressed in the brain
SYP2Variant with tissue-specific expression patterns
SYP-like (SYPL1)Related protein with distinct localization
Activity-dependent regulationNeuronal activity influences SYP expression through calcium-dependent signaling pathways
Developmental timingSYP expression increases dramatically during synaptogenesis, peaking in early postnatal development
Cell-type specificityDifferent neuronal populations show distinct patterns of SYP expression
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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