disease-classification

Understanding Entity Pages

This page aggregates everything SciDEX knows about disease-classification: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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graph TD
    disease["disease"]
    PARKINSON_S["PARKINSON'S"]
    disease -->|"activates"| PARKINSON_S
    BDNF["BDNF"]
    disease -->|"associated_with"| BDNF
    SELECTIVE_AUTOPHAGY["SELECTIVE AUTOPHAGY"]
    disease -->|"activates"| SELECTIVE_AUTOPHAGY
    HSPB8["HSPB8"]
    disease -->|"activates"| HSPB8
    Autophagy["Autophagy"]
    disease -->|"activates"| Autophagy
    RAPAMYCIN["RAPAMYCIN"]
    disease -->|"inhibits"| RAPAMYCIN
    Lysosomal_Degradation["Lysosomal Degradation"]
    disease -->|"associated_with"| Lysosomal_Degradation
    APOE["APOE"]
    disease -->|"regulates"| APOE
    PTEN["PTEN"]
    disease -->|"activates"| PTEN
    CENTRAL_NERVOUS_SYSTEM["CENTRAL NERVOUS SYSTEM"]
    disease -->|"protects_against"| CENTRAL_NERVOUS_SYSTEM
    Hippocampus["Hippocampus"]
    disease -->|"associated_with"| Hippocampus
    HSPA1A["HSPA1A"]
    disease -->|"expressed_in"| HSPA1A
    style disease fill:#ef5350,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
    style PARKINSON_S fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0
    style BDNF fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
    style SELECTIVE_AUTOPHAGY fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0
    style HSPB8 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
    style Autophagy fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0
    style RAPAMYCIN fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0
    style Lysosomal_Degradation fill:#1b5e20,stroke:#333,stroke-width:1px,color:#e0e0e0
    style APOE fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
    style PTEN fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
    style CENTRAL_NERVOUS_SYSTEM fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0
    style Hippocampus fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0
    style HSPA1A fill:#4a1a6b,stroke:#333,stroke-width:1px,color:#e0e0e0