Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about disease-prevalence: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
graph TD
disease["disease"]
GPX4["GPX4"]
disease -->|"inhibits"| GPX4
ATAXIN_2["ATAXIN-2"]
disease -->|"inhibits"| ATAXIN_2
GSTP1["GSTP1"]
disease -->|"associated_with"| GSTP1
cGAS_STING_pathway["cGAS-STING pathway"]
disease -->|"activates"| cGAS_STING_pathway
WDR45["WDR45"]
disease -->|"activates"| WDR45
DJ_1["DJ-1"]
disease -->|"causes"| DJ_1
HMGCR["HMGCR"]
disease -->|"inhibits"| HMGCR
STEM_CELLS["STEM CELLS"]
disease -->|"regulates"| STEM_CELLS
Tgf["Tgf-Beta"]
disease -->|"associated_with"| Tgf
PRKN["PRKN"]
disease -->|"causes"| PRKN
LIPID_METABOLISM["LIPID METABOLISM"]
disease -->|"associated_with"| LIPID_METABOLISM
CHIP["CHIP"]
disease -->|"activates"| CHIP
style disease fill:#ef5350,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
style GPX4 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style ATAXIN_2 fill:#4a1a6b,stroke:#333,stroke-width:1px,color:#e0e0e0
style GSTP1 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style cGAS_STING_pathway fill:#1b5e20,stroke:#333,stroke-width:1px,color:#e0e0e0
style WDR45 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style DJ_1 fill:#4a1a6b,stroke:#333,stroke-width:1px,color:#e0e0e0
style HMGCR fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style STEM_CELLS fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0
style Tgf fill:#1b5e20,stroke:#333,stroke-width:1px,color:#e0e0e0
style PRKN fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style LIPID_METABOLISM fill:#1b5e20,stroke:#333,stroke-width:1px,color:#e0e0e0
style CHIP fill:#4a1a6b,stroke:#333,stroke-width:1px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||