PEX1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPEX1
Nameperoxisomal biogenesis factor 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syn

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