Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ent-prot-d498ecaa: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| h-b6167641 | targeted_by | hypothesis | 1.00 |
| h-0c9e2166ed | targeted_by | hypothesis | 1.00 |
| h-494ad6afe0 | targeted_by | hypothesis | 1.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| h-0c9e2166ed | targets | hypothesis | 1.00 |
| h-494ad6afe0 | targets | hypothesis | 1.00 |
| h-b6167641 | targets | hypothesis | 1.00 |
| 39294194 | is compartmentalized within | paper | 0.90 |
| 39294194 | is implicated in | paper | 0.90 |
| 39294194 | has been implicated in | paper | 0.90 |
| 39294194 | exhibits hallmark neuropathology in | paper | 0.90 |
| 39294194 | compartmentalized within | paper | 0.90 |
| 20948999 | is a principle component of inclusions in | paper | 0.90 |
| 20948999 | associates with stress granules by interacting with via | paper | 0.90 |
| 20948999 | resides in but aberrantly processes to form cytoplasmic inclusions in | paper | 0.90 |
| 39294194 | is localized in | paper | 0.90 |
| 20948999 | associates with stress granules via interacting with | paper | 0.90 |
| 21358643 | directly binds and enhances splicing of | paper | 0.90 |
| 31031584 | undergoes | paper | 0.90 |
| 21358643 | binds to | paper | 0.90 |
| 21358643 | autoregulates | paper | 0.90 |
| 35495061 | controls through negative feedback loop | paper | 0.90 |
| 40707625 | stabilizes | paper | 0.90 |
| 37777806 | exhibits pathological synergy with | paper | 0.90 |
| 35178571 | enhances | paper | 0.90 |
| 35178571 | promotes | paper | 0.90 |
| 35178571 | causes | paper | 0.90 |
| 23092511 | is required for | paper | 0.90 |
| 23092511 | regulates | paper | 0.90 |
| 34378050 | redistributes to | paper | 0.90 |
| 41120750 | regulates | paper | 0.90 |
| 41498748 | colocalized and bound | paper | 0.90 |
| 41498748 | ubiquitinates | paper | 0.90 |
| 35767949 | mediates proper splicing of | paper | 0.90 |
| 24686783 | interacts with | paper | 0.90 |
| 36922834 | mislocalises from | paper | 0.90 |
| 20948999 | regulates mRNA metabolism by interacting with | paper | 0.60 |
| 38079474 | has a primary role in | paper | 0.60 |
| 41120750 | has emerged as a repressor of | paper | 0.60 |
| 24113586 | is considered to be a major disease protein in | paper | 0.60 |
| 39294194 | may serve analogous functional roles in | paper | 0.30 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ent-prot-d498ecaa in their description or question text
No additional research found