LOC110386948

biological-region External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolLOC110386948
NameCYP19A1 promoter I.4
Typebiological-region
Sourcemygene

Summary

This region represents an alternate promoter of the CYP19A1 (cytochrome P450 family 19 subfamily A member 1) gene, also known as aromatase. This promoter is expressed in adipose and skin cells, and is regulated by glucocorticoids, Jak/Stat signaling, transforming growth factor beta, and tumor necrosis factor alpha. AP-1 family factors, RAR related orphan receptor A, and runt related transcription factor 2 bind to recognition sites in this region and mediate promoter activation. [provided by RefS

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