C1orf56

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolC1orf56
Namechromosome 1 open reading frame 56
Typeprotein-coding
Sourcemygene

Summary

This gene is a proto-oncogene whose promoter is methylated by DNA methyltransferase 3B (DNMT3B), which represses the proto-oncogene. However, a catalytically inactive isoform of DNMT3B is overexpressed in lymphomas, leading to hypomethylation of the proto-oncogene's promoter and derepression of the proto-oncogene. [provided by RefSeq, Sep 2016].

This is an externally resolved entity

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