Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about lysosomal pH restoration: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| V-ATPase enhancement | causes (enhances proton pumping to restore acidic pH in ly) | protein | 0.75 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Lysosomal pH Restoration Upstream of TFEB | 0.458 | neurodegeneration | Does TFEB dysfunction cause neurodegener |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-03 | 7 hypotheses Top: 0.510
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Protective Role of Purslane Supplementation Against Cadmium-Induced Renal and Gi [PMID:40877613] | Alsubaie N, Abd-Elhakim YM, Mohamed AA, | Biol Trace Elem Res | 2026 | 0 |
| Ginsenoside Rg5 inhibits colorectal cancer, at least partially by blocking the l [PMID:41639226] | Guo X, Sun R, Su Y, Qin Q, Liu Y et al. | Sci Rep | 2026 | 0 |
| Real-time visualization of drug-target interactions in native subcellular microe [PMID:41756019] | Wang R, Yuan Y, Shao H, Sun Y, Lai C et | J Pharm Anal | 2026 | 0 |