Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about miR-143/145 cluster: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| VSMC differentiation | regulates | process | 0.70 |
| P2RY12 | inhibits | gene | 0.50 |
| VSMC phenotypic switching | regulates | process | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| miR-143/145 Cluster Dysregulation Derepresses P2RY12 Transcr | 0.520 | neurodegeneration | What determines P2RY12 receptor expressi |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-07 | 7 hypotheses Top: 0.650
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning miR-143/145 cluster in their description or question text
No additional research found