SLC5A7

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolSLC5A7
Namesolute carrier family 5 member 7
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implic

This is an externally resolved entity

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