Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about plasma p-tau217: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| amyloid PET positivity | biomarker_for | phenotype | 0.90 |
| treatment response | biomarker_for | phenotype | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| amyloid plaque burden | causes | process | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Plasma p-tau217-Triggered Exosome Dosing Maximizes lncRNA-00 | 0.323 | molecular neurobiology | View |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-16 | 1 hypotheses Top: 0.577
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Microglia activation orchestrates CXCL10-mediated CD8+ T cell recruitment to pro [PMID:40404995] | Groh J, Feng R, Yuan X, Liu L, Klein D, | Nature neuroscience | 2025 | 0 |
| Sirt6 protects retinal ganglion cells and optic nerve from degeneration during a [PMID:38659223] | Xia F, Shi S, Palacios E, Liu W, Buscho | Molecular therapy : the journa | 2024 | 0 |
| From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Bl [PMID:28840449] | Tucker D, Lu Y, Zhang Q | Molecular neurobiology | 2018 | 0 |
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.50 · 2026-04-26
closed · Rounds: 4 · Score: 0.76 · 2026-04-16
Hypotheses and analyses mentioning plasma p-tau217 in their description or question text
No additional research found