disease

shy-drager-syndrome

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about shy-drager-syndrome: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Disease Info
1960Milton Shy and Glenda Drager described a syndrome of autonomic failure with parkinsonism[@shy1960a]
1969The term "Shy-Drager syndrome" came into common use following detailed clinical descriptions[@bannister1972]
1989Multiple system atrophy (MSA) was proposed as an umbrella term encompassing Shy-Drager syndrome, striatonigral degeneration, and olivopontocerebellar atrophy[@graham1989]
1998Discovery of α-synuclein in glial cytoplasmic inclusions established the proteinaceous basis of MSA[@spillantini1997]
2008Second consensus criteria for MSA established modern diagnostic framework[@gilman2008]
DatabasesOMIMOrphanetClinicalTrialsPubMed

Wiki Pages (8)

Knowledge base pages for this entity

Canonical Page

Shy-Drager Syndrome

disease · 3312 words

Synucleinopathy Mechanism

mechanism · 4870 words

Shy-Drager Syndrome

disease · 3389 words

Diseases

index · 3070 words

Multiple System Atrophy (MSA) Pathway

mechanism · 2928 words

Magnocellular Preoptic Nucleus

cell · 878 words

Pathway Diagram

graph TD
    shy_drager_syndrome["<b>shy-drager-syndrome</b>"]
    info["No connections yet"]
    shy_drager_syndrome -.-> info
    style shy_drager_syndrome fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#4fc3f7
    style info fill:#2a2a2a,stroke:#666,stroke-dasharray:5,color:#999

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

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No targeting hypotheses

Mentioning Analyses (0)

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Experiments (0)

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ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
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Related Papers (0)

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Debates (0)

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