Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about tau phagocytosis: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| GluN2B-CX3CL1 Axis Controls Microglial Tau Phagocytosis | 0.761 | neuroscience | GluN2B-Mediated Thalamocortical Control |
| Microglial TREM2-Mediated Tau Phagocytosis Impairment | 0.676 | neuroscience | Circuit-level neural dynamics in neurode |
| GluN2B-Mediated Microglial Activation and Tau Phagocytosis | 0.380 | neuroscience | Circuit-level neural dynamics in neurode |
Scientific analyses that reference this entity
neuroscience | 2026-04-28 | 7 hypotheses Top: 0.808
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Differential vulnerability of hippocampal CA3-CA1 synapses to Aβ. [PMID:35379353] | Unknown | Acta Neuropathol Commun | 2022 | 0 |
| Tau accumulation triggers STAT1-dependent memory deficits by suppressing NMDA re [PMID:31085626] | Unknown | EMBO Rep | 2019 | 0 |
| Chronic brain inflammation causes a reduction in GluN2A and GluN2B subunits of N [PMID:24761931] | Unknown | Mol Brain | 2014 | 0 |
| Activation of NR1a/NR2B receptors by soluble factors from APP-stimulated monocyt [PMID:15212844] | Unknown | Neurobiol Aging | 2004 | 0 |
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning tau phagocytosis in their description or question text
No additional research found