The debate focused on astrocyte-to-neuron transfer but did not address what molecular signals control transfer direction or why certain cell pairs preferentially exchange mitochondria. This knowledge gap limits precision therapeutic approaches. Source: Debate session sess_SDA-2026-04-01-gap-20260401231108 (Analysis: SDA-2026-04-01-gap-20260401231108)
Landscape Summary: What determines the directionality and selectivity of mitochondrial transfer between specific cell types? is a 0.75 priority gap in cell-biology. It has 0 linked hypotheses with average composite score 0.000. Status: open.
Colonna, Sevlever, et al. (TREM2 biology)
What determines the directionality and selectivity of mitochondrial transfer between specific cell types? — INVOKE-2 (completed)
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