The study shows high-neural tumors have increased functional connectivity on neuroimaging, but the causal relationship between neural signature and connectivity patterns remains unexplained. This gap limits understanding of how tumor-neural interactions affect brain network function. Gap type: unexplained_observation Source paper: A prognostic neural epigenetic signature in high-grade glioma. (None, None, PMID:38760585)
Landscape Summary: Why do high-neural glioblastomas exhibit increased functional connectivity and what drives this phenomenon? is a 0.75 priority gap in neuro-oncology. It has 0 linked hypotheses with average composite score 0.000. Status: open.
Colonna, Sevlever, et al. (TREM2 biology)
Why do high-neural glioblastomas exhibit increased functional connectivity and what drives this phenomenon? — INVOKE-2 (completed)
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