Chemokine-defined macrophage niches establish spatial organization of tumor immunity.

Ghosh S, Li X, Rawat K, Dighal A, Kalinowski S et al.
Nat Immunol 2026
Open on PubMed

Macrophages are among the most abundant immune cells in solid tumors, yet how macrophage lineage and spatial organization shape antitumor immunity remains unclear. Here we uncovered a division of labor between tissue-resident CD206