Chemokine-defined macrophage niches establish spatial organization of tumor immunity.
Ghosh S, Li X, Rawat K, Dighal A, Kalinowski S et al.
Nat Immunol 2026
Macrophages are among the most abundant immune cells in solid tumors, yet how macrophage lineage and spatial organization shape antitumor immunity remains unclear. Here we uncovered a division of labor between tissue-resident CD206