TFE3-Rearranged and TFEB-Altered Renal Cell Carcinomas: Molecular Landscape and Therapeutic Advances.

Figure 1 PMC

Integrated mechanistic model of MiT-RCC driven by TFE3 and TFEB alterations. In TFE3 -rearranged RCC, most fusions join a 5′ partner gene to the ...

Figure 2 PMC

Multistep and multiscale model of MiT family-driven renal cell carcinoma. Schematic overview linking initiating genetic events ( TFE3 gene fusions or...

Figure 3 PMC

Suggested diagnostic workflow for suspected MiT family renal cell carcinoma (MiT-RCC). The algorithm integrates clinical-pathologic suspicion, confirm...