[Exchange] Enrich next 5 thin hypotheses with descriptions, pathways, clinical trials
ID: ea545379-544
Priority: 87
Type: one_shot
Status: complete
Goal
Enrich 5 thin hypotheses with deep descriptions, pathway diagrams, and clinical trials data.
Acceptance Criteria
☑ 5 thin hypotheses identified and enriched with 5000+ char descriptions
☑ Each hypothesis has 6 evidence citations with PMIDs
☑ Each hypothesis has pathway diagram
☑ Each hypothesis has 3-4 clinical trial references
☑ All hypothesis pages load successfully (HTTP 200)
☑ Work log updated with timestamped entry
Work Log
2026-04-02T12:30 — Slot 7
- Identified 5 thinnest hypotheses (desc <200 chars, no clinical_trials, no pathway_diagram):
- h-5dbfd3aa: Heat Shock Protein 70 Disaggregase Amplification (HSPA1A)
- h-ec731b7a: Phase-Separated Organelle Targeting (G3BP1)
- h-82922df8: Matrix Stiffness Normalization via Targeted Lysyl Oxidase Inhibition (LOX)
- h-69919c49: PARP1 Inhibition Therapy (PARP1)
- h-97aa8486: Stress Granule Phase Separation Modulators (G3BP1)
- Created enrich_thin_5.py with deep descriptions (5700-6900 chars each), 6 citations per hypothesis, pathway diagrams, and 3-4 clinical trials per hypothesis
- Ran script successfully: all 5 hypotheses enriched
- All hypothesis pages return HTTP 200