🎯 Drug Targets

Browse 2 drug targets with druggability analysis, composite scores, and clinical context

2
Targets
2
High Druggability
0.67
Avg Score
15
Target Classes
Druggability Distribution
High: 2Medium: 0Low: 0Unknown: 0
Avg druggability score: 0.775
Clinical Pipeline
Approved: 1Phase III: 1Phase II: 0Phase I: 0Preclinical: 0
Total compounds: 3 · Approved: 1
Filtered by: class=signaling_protein, druggability=High — 2 results
BCL2L1 BCL2 Like 1 Phase 4
Signaling Protein High Druggability
Score
0.68
Drug.
0.80
Safety
0.40
Drugs
2
Hyps
1
Papers
31
Small molecule inhibitor of anti-apoptotic protein function
RAB7A Ras-related protein Rab-7a Phase 3
Signaling Protein High Druggability
Score
0.67
Drug.
0.75
Safety
0.30
Drugs
1
Hyps
1
Papers
28
RAB7A inhibitors or modulators would block or enhance GTPase-mediated late endosome and lysosome trafficking, disrupting autophagy flux and lysosomal degradation pathways. This can either impair pathogenic protein clearance (in certain cancers) or restore lysosomal function (in storage disorders and neurodegeneration).