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Drug Targets
🎯 Drug Targets
Browse 2 drug targets with druggability analysis, composite scores, and clinical context
2
Targets
2
High Druggability
0.67
Avg Score
15
Target Classes
Druggability Distribution
High:
2
Medium:
0
Low:
0
Unknown:
0
Avg druggability score:
0.775
Clinical Pipeline
Approved:
1
Phase III:
1
Phase II:
0
Phase I:
0
Preclinical:
0
Total compounds:
3
· Approved:
1
Search
Class
All Classes
Enzyme
(35)
Signaling Protein
(25)
Structural Protein
(17)
Protein
(16)
Gpcr
(13)
Ion Channel
(12)
Transcription Factor
(11)
Receptor
(11)
Ligand
(10)
Transporter
(8)
Epigenetic Regulator
(8)
Kinase
(7)
Protease
(4)
Other
(4)
Chaperone
(4)
Druggability
All Druggability
Low
(100)
Medium
(62)
High
(14)
Undruggable
(6)
other
(3)
Sort
Score
Druggability
Gene A-Z
Market Price
Filtered by: class=signaling_protein, druggability=High — 2 results
BCL2L1
BCL2 Like 1
Phase 4
Signaling Protein
High Druggability
Score
0.68
Drug.
0.80
Safety
0.40
Drugs
2
Hyps
1
Papers
31
Small molecule inhibitor of anti-apoptotic protein function
RAB7A
Ras-related protein Rab-7a
Phase 3
Signaling Protein
High Druggability
Score
0.67
Drug.
0.75
Safety
0.30
Drugs
1
Hyps
1
Papers
28
RAB7A inhibitors or modulators would block or enhance GTPase-mediated late endosome and lysosome trafficking, disrupting autophagy flux and lysosomal degradation pathways. This can either impair pathogenic protein clearance (in certain cancers) or restore lysosomal function (in storage disorders and neurodegeneration).