| Gene Symbol | ABCAB1 |
| Full Name | ATP-Binding Cassette Transporter A1 |
| Chromosome | 9q31.1 |
| Protein Type | Transporter |
| Function | encodes a 2,261 amino acid membrane protein that serves as the primary regulator of cellular cholesterol and phospholipid efflux to apolipoproteins. |
| Primary Expression | astrocytes and microglia, where it supports: |
| Subcellular Localization | ** | Plasma Membrane, Golgi Apparatus | [@lefterov2010] |
| Amino Acids | 261 aa |
| UniProt ID | O95477 |
| NCBI Gene ID | 19 |
| Ensembl ID | ENSG00000165029 |
| OMIM | 205400 |
| GeneCards | ABCAB1 |
| Human Protein Atlas | ABCAB1 |
| Two Transmembrane Domains (TMDs) | Each TMD contains 6 transmembrane helices that span the lipid bilayer, forming the translocation pathway PMID: 11021969 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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