gene 2,366 words KG: ABCG1 2026-03-27
section:geneskind:genetopic:alzheimerstopic:parkinsons
Contents

ABCG1 Gene

🧬 Gene Info
Gene SymbolABCG1
Full NameATP-Binding Cassette Subfamily G Member 1
Chromosome21q22.3
Protein TypeTransporter
Functionis a critical lipid transporter protein that plays a fundamental role in cellular cholesterol and phospholipid homeostasis.
Primary Expressionneurons, astrocytes, microglia, and oligodendrocytes, where it regulates brain lipid homeostasis and protects against neurodegeneration[@tansley2007][
Molecular Weight67 kDa
Exons23
PathwaysCholesterol
UniProt IDP45878
NCBI Gene ID26273
Ensembl IDENSG00000160179
OMIM603076
GeneCardsABCG1
Human Protein AtlasABCG1
Associated DiseasesAD, ALS, AMI, ARM, Alzheimer
Known Drugs/Compoundsquercetin
InteractionsSQSTM1, ABCA1, APOE, LOX, P2RY12, LC3
KG Connections251 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph