| Gene Symbol | ADGRV1 |
| Aliases | GPR98 |
| Protein Type | Gene |
| Function | is a member of the adhesion GPCR family, characterized by a large extracellular N-terminal region containing multiple calx-beta domains and a GPS (GPCR proteolysis site) domain. |
| Primary Expression | the cerebellum, hippocampus, and cerebral cortex, where it may function in synaptic organizatio |
| Subcellular Localization | retinal photoreceptor cells (2017)](https://doi.org/10.1016/j.exer.2017.07.012) |
| Molecular Weight | 690 kDa |
| Amino Acids | 6000 aa |
| Ensembl ID | ENSG00000164199 |
| GeneCards | ADGRV1 |
| Human Protein Atlas | ADGRV1 |
| Sensorineural Hearing Loss | Progressive hearing loss beginning in childhood |
| Retinitis Pigmentosa | Progressive retinal degeneration leading to tunnel vision and blindness |
| Vestibular Function | Typically normal vestibular function in USH2C |
| Febrile Seizures | Some variants may lower seizure threshold |
| Associated Diseases | epilepsy and autism spectrum disorder |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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