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Owkin — AI for Drug Discovery

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Related Hypotheses (202)

Rare TREM2-TYROBP pathway variants complement standard PRS b
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GluN2B-Mediated Microglial Activation and Tau Phagocytosis
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APOE4-driven loss of neuronal PI(4,5)P2 bridges ganglioside-
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CRP-Mediated CCR2+ Monocyte Recruitment Drives Microglial IL
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ABCA1 Upregulation via LXRβ Agonism to Enhance Cholesterol E
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CD38 Inhibition to Preserve NAD+ Pools and Prevent PARP1-Med
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CD38 Inhibition to Prevent NAD+ Depletion and Restore Cellul
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Dynamic Blood-Based Exosome Panel for Real-Time Neuroinflamm
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LXRα-Selective Agonism to Enhance Hepatic APOE Secretion and
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Closed-loop tACS targeting EC-II SST interneurons to block t
Score: 0.99
Closed-loop focused ultrasound targeting EC-II SST interneur
Score: 0.98
Closed-loop optogenetic targeting PV interneurons to restore
Score: 0.95
Closed-loop focused ultrasound targeting CA1 PV interneurons
Score: 0.95
Closed-loop transcranial focused ultrasound targeting EC-II
Score: 0.94
Closed-loop tACS targeting EC-II PV interneurons to suppress
Score: 0.93
p38α Inhibitor and PRMT1 Activator Combination to Restore Ph
Score: 0.88
Closed-loop focused ultrasound targeting EC-II PV interneuro
Score: 0.86
Closed-loop tACS targeting EC-II parvalbumin interneurons to
Score: 0.85
Sequential Iron Chelation (Deferoxamine) and GPX4 Restoratio
Score: 0.84
Closed-loop transcranial focused ultrasound to restore hippo
Score: 0.83
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