biomarker 1,092 words KG: ent-prot-1e3aff6a 2026-03-24
kind:biomarkersection:biomarkersstate:published
Contents

Tau Seed Amplification Assays (Tau-RT-QuIC)

🔬 Protein Info
Gene Symbolent-prot-1e3aff6a
SCA (Seeding Conversion Assay)Modified RT-QuIC variant
dRT-QuICDigital RT-QuIC for absolute quantification
FRET-based assaysFluorescence resonance energy transfer detection
Sensitivity85-95% in AD patients
Specificity90-100% vs. healthy controls
CorrelationSeed activity correlates with CSF p-tau and cognitive scores
Preclinical detectionPositive in MCI and preclinical stages
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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