| Dopaminergic dysfunction | Reduced dopaminergic signaling in the putamen and caudate nucleus |
| Cholinergic deficits | Loss of cholinergic neurons in the nucleus basalis of Meynert |
| GABAergic dysfunction | Reduced inhibitory modulation in motor circuits |
| Serotonergic alterations | Contributing to motor and non-motor features |
| Databases | OMIMOrphanetClinicalTrialsPubMed |
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