| Gene Symbol | ent-gene-a180355d |
| Function | ### GABAergic Signaling |
| Cerebral Cortex | Cortical interneurons, particularly parvalbumin (PV) and somatostatin (SST) expressing neurons |
| Striatum | GABAergic medium spiny neurons (MSNs) and interneurons |
| Basal Forebrain | Cholinergic projection neurons (basal forebrain cholinergic neurons - BFCNs) |
| Hippocampus | GABAergic hippocampal interneurons |
| Olfactory Bulb | GABAergic granule and periglomerular cells |
| Thalamus | Thalamic reticular nucleus (TRN) neurons |
| Neural progenitor specification | ARX is expressed in neural progenitor cells destined to become interneurons |
| Cell cycle exit | Promotes transition from proliferating progenitors to post-mitotic neurons |
| Migration | Essential for tangential migration of GABAergic interneurons from the medial ganglionic eminence (MGE) |
| GABAergic fate | Drives expression of GABA synthesis enzymes (GAD1, GAD2) and vesicular GABA transporter (VGAT) |
| Cholinergic fate | ARX+ progenitors give rise to cholinergic neurons in the basal forebrain |
| Subtype specification | Regulates expression of interneuron subtype markers (PV, SST, VIP, CR) |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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